The Laboratory of Biomaterials and Tissue Engineering

Laboratory description/carried out research

The work carried out in the Laboratory of Biomaterials and Tissue Engineering includes the development of new solutions for the fabrication of tissue scaffolds, local delivery systems for bioactive substances (including drugs), and various types of structures based on biomaterials made of functional polymers, natural polymers, and composites, as well as metals, for the application in tissue engineering, regenerative and implantable medicine, and broadly defined biotechnology.

In addition, our team is involved in the synthesis of polymers, organic and inorganic bio- and nanomaterials, hybrid materials, biodegradable composites based on natural polymers, metallic, non-metallic, polymeric nanoparticles, smart materials that respond to external stimuli such as temperature, pH changes, magnetic fields or UV light, and polypeptide/polymersynthetic conjugates.

The conducted activities focus on both the design and manufacture, as well as characterization of the physical and chemical properties of the obtained structures using advanced research techniques. Studies on their biocompatibility and their applicability in vitro are also carried out.

 

The conducted research concerns mainly:

  • fabrication of three-dimensional polymeric scaffolds for applications in regenerative medicine, with particular emphasis on fiber-based structures fabricated by electrospinning
  • in vitro and in vivo characterization of biomaterials
  • fabrication of nonwovens/membranes for biotechnological applications
  • synthesis of polymers, organic and inorganic bio- and nanomaterials, hybrid materials, biodegradable composites based on natural polymers
  • synthesis of intelligent materials responding to external stimuli
  • synthesis of metallic, non-metallic, polymeric nanoparticles, smart materials, polypeptide/polymersynthetic conjugates
  • creation of new inorganic-organic formulations having the ability to carry therapeutics based on selective targeting modification of drug formulations to increase their bioavailability, biocompatibility and release time

Equipment / devices

  • HPLC chromatograph with PDA detector
  • Rotational-oscillatory rheometer with UV light crosslinking attachment
  • Synthesis station
  • Workstations for producing fibrous structures by electrospinning from solution

Employees

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