We are pleased to announce that the CEZAMAT research team, in cooperation with the Department of Chemistry at Warsaw University of Technology, has won funding under the “Grant for Prototype” competition for the development of a groundbreaking microfluidic technology. The developed MicroGrow tool has        the potential to revolutionize research processes, enabling more precise modeling of human organs in laboratory conditions, which will significantly accelerate the development of new therapies and drugs.

The authors of the project are:

• Agnieszka Żuchowska, PhD Eng. – (Faculty of Chemistry,WUT),
• Patrycja Baranowska PhD Eng. – (Cezamat WUT),
• Elżbieta Jastrzębska, PhD Eng. – (Cezamat WUT, Faculty of Chemistry WUT, prof. of WUT).

MicroGrow technology is an innovative approach to cell culture, enabling the creation of spatial (3D) models of human organs in laboratory conditions, which accelerates the evaluation of the effectiveness of new drugs and toxicity of compounds. The goal of the project is to develop the CellSphereMultiFlow tool and methodology for its use, which will allow:

• creation of three-dimensional cell spheroids that more faithfully reproduce natural in vivo conditions than traditional cell models,
• long-term cell culture under flow-through conditions without the need for expensive and complex equipment (e.g., peristaltic pumps),
• reducing biological waste and reagent consumption by working with micro-volumes,
• reducing costs and errors due to manual pipetting procedures.

The proposed tool, based on microfluidic technologies, enables more advanced in vitro testing, which translates into an increased likelihood of correctly assessing an organism’s response to drugs under laboratory conditions, while minimizing animal testing, according to the 3R (replacement, reduction, refinement) principle.