Biography
She received an MSc Eng in Biotechnology from Warsaw University of Technology in 2020. Now she is a PhD student and realizes work in the title “Regenerative properties of stem cells in various cardiac hypoxia models.” Her main research interest is the application of regenerative medicine using stem cells and tissue engineering. She is carrying out her PhD study at the Faculty of Chemistry of the Warsaw University of Technology, at the M. Nencki Institute of Experimental Biology of the Polish Academy of Sciences, and at CEZAMAT of the Warsaw University of Technology. Since 2020 employed as a contractor in the SONATA BIS 9 NCN project. In 2024, an applicant and principal researcher in IDUB YOUNG II with the title “Differentiation and maturation of cardiomyocytes and cardiac organoids derived from induced pluripotent stem cells in a microsystem under flow and static conditions.”
Research areas
- In vitro cell culture and analysis, including cultures of human stem cells (iPSCs) and primary human, mouse, and rat cell lines.
- Experience working with microfluidic systems and nanofibers.
- Familiarity with techniques: RT-PCR, confocal microscopy, PCR, gel electrophoresis, Western blot
Selected Publications
- Iwoń Z, Krogulec E, Kierlańczyk A, Baranowska P, Łopianiak I, Wojasiński M, Jastrzębska E. Improving rodents and humans cardiac cell maturity in vitro through polycaprolactone and polyurethane nanofibers. Biomed Mater. 2024 Feb 12;19(2). doi: 10.1088/1748-605X/ad240a
- D. Kołodziejek, Urszula Sierańska, Zuzanna Iwoń, Iwona Łopianiak, Ewelina Krogulec, Michał Wojasiński, Elżbieta Jastrzębska, ‘Cardiac Tissue Modeling Using Flow Microsystems and Nanofiber Mats: Evaluating Hypoxia-Induced Cellular and Molecular Changes’, Sensors and Actuators B: Chemical, p. 135169, Dec. 2023, doi: 10.1016/j.snb.2023.135169
- Iwoń Z, Krogulec E, Kierlańczyk A, Wojasiński M, Jastrzębska E. Hypoxia and re-oxygenation effects on human cardiomyocytes cultured on polycaprolactone and polyurethane nanofibrous mats. J Biol Eng. 2024 Jun 6;18(1):37. doi: 10.1186/s13036-024-00432-5
- Iwoń, Z., Krogulec, E., Tarnowska, I. et al. Maturation of human cardiomyocytes derived from induced pluripotent stem cells (iPSC-CMs) on polycaprolactone and polyurethane nanofibrous mats. Sci Rep 14, 12975 (2024). oi: 10.1038/s41598-024-63905-z